TITLE

Multidrug-resistant Mycobacterium tuberculosis in HIV-infected persons, Peru

AUTHOR(S)
Campos, Pablo E.; Suarez, Pedro G.; Sanchez, Jorge; Zavala, David; Arevalo, Jorge; Ticona, Eduardo; Nolan, Charles M.; Hooton, Thomas M.; Holmes, King K.
PUB. DATE
December 2003
SOURCE
Emerging Infectious Diseases;Dec2003, Vol. 9 Issue 12, p1571
SOURCE TYPE
Academic Journal
DOC. TYPE
journal article
ABSTRACT
During 1999 to 2000, we identified HIV-infected persons with new episodes of tuberculosis (TB) at 10 hospitals in Lima, Peru, and a random sample of other Lima residents with TB. Multidrug-resistant (MDR)-TB was documented in 35 (43%) of 81 HIV-positive patients and 38 (3.9%) of 965 patients who were HIV-negative or of unknown HIV status (p < 0.001). HIV-positive patients with MDR-TB were concentrated at three hospitals that treat the greatest numbers of HIV-infected persons with TB. Of patients with TB, those with HIV infection differed from those without known HIV infection in having more frequent prior exposure to clinical services and more frequent previous TB therapy or prophylaxis. However, MDR-TB in HIV-infected patients was not associated with previous TB therapy or prophylaxis. MDR-TB is an ongoing problem in HIV-infected persons receiving care in public hospitals in Lima and Callao; they represent sentinel cases for a potentially larger epidemic of nosocomial MDR-TB.
ACCESSION #
11679225

 

Related Articles

  • Natural Terpenes Influence the Activity of Antibiotics against Isolated Mycobacterium tuberculosis. Sieniawska, Elwira; Swatko-Ossor, Marta; Sawicki, Rafał; Skalicka-Woźniak, Krystyna; Ginalska, Grazyna // Medical Principles & Practice;Mar2017, Vol. 26 Issue 2, p108 

    Objective: In this study, we aimed to describe the influence of natural terpenes on the antimycobacterial activity of first-line tuberculostatic drugs against isolated Mycobacterium tuberculosis.Materials and Methods: The natural terpenes used in this study were...

  • E-Test: An Alternative Method for Susceptibility Testing of Mycobacterium tuberculosis. S. Akcali; C. Cicek; S. Surucuoglu; B. Ozbakkaloglu // Medical Principles & Practice;Jul/Aug2005, Vol. 14 Issue 4, p264 

    Objective: The purpose of this study was to compare the agar proportion method with the E-test method for susceptibility testing of Mycobacterium tuberculosis.Materials and Methods: A total of 100 isolates were tested for isoniazid, rifampin, streptomycin and ethambutol susceptibility using an...

  • Pyrazinamide resistance-conferring mutations in pncA and the transmission of multidrug resistant TB in Georgia. Sengstake, Sarah; Bergval, Indra L.; Schuitema, Anja R.; de Beer, Jessica L.; Phelan, Jody; de Zwaan, Rina; Clark, Taane G.; van Soolingen, Dick; Anthony, Richard M. // BMC Infectious Diseases;7/12/2017, Vol. 17, p1 

    Background: The ongoing epidemic of multidrug-resistant tuberculosis (MDR-TB) in Georgia highlights the need for more effective control strategies. A new regimen to treat MDR-TB that includes pyrazinamide (PZA) is currently being evaluated and PZA resistance status will largely...

  • Sequence analysis for detection of first-line drug resistance in Mycobacterium tuberculosis strains .from a high-incidence setting.  // BMC Microbiology;2012, Vol. 12 Issue 1, p90 

    The article discusses a study which aims to identify the first-line drug resistance in Mycobacterium tuberculosis (TB) strains from a high-incidence setting in Sierra Leone. It states that 97 strains were analyzed for mutations and 50 were found to be either mono- or poly-resistant to rifampin,...

  • Discordance in Mycobacterium tuberculosis Rifampin Susceptibility. Kalokhe, Ameeta S.; Shafiq, Majid; Lee, James C.; Metchock, Beverly; Posey, James E.; Ray, Susan M.; Anderson, Albert; Wang, Yun F.; Nguyen, Minh Ly T. // Emerging Infectious Diseases;Mar2012, Vol. 18 Issue 3, p537 

    The article discusses the case of a 45-year-old homeless woman with acquired immune deficiency syndrome (AIDS) who experienced pulmonary tuberculosis (TB) relapse with an associated resistance to antituberculous drugs isoniazid (INH) and rifampin (RIF). Her symptoms included fever, night sweats,...

  • Mycobacterium tuberculosis spoligotypes and drug susceptibility pattern of isolates from tuberculosis patients in peri-urban Kampala, Uganda. Asiimwe, Benon B.; Ghebremichael, Solomon; Kallenius, Gunilla; Koivula, Tuija; Joloba, Moses L. // BMC Infectious Diseases;2008, Vol. 8 Issue 1, Special section p1 

    Background: The poor peri-urban areas of developing countries with inadequate living conditions and a high prevalence of HIV infection have been implicated in the increase of tuberculosis (TB). Presence of different lineages of Mycobacterium tuberculosis has been described in different parts of...

  • Drug-susceptibility Patterns of Mycobacterium tuberculosis in Mpumalanga Province, South Africa: Possible Guiding Design of Retreatment Regimen. Green, E.; Obi, C. L.; Nchabeleng, M.; De Villiers, B. E.; Sein, P. P.; Letsoalo, T.; Hoosen, A. A.; Bessong, P. O.; Ndip, R. N. // Journal of Health, Population & Nutrition;Feb2010, Vol. 28 Issue 1, p7 

    Multidrug-resistant tuberculosis (MDR-TB) has been a cause of concern in both developed and developing countries. The prevalence of drug resistance in Mycobacterium tuberculosis (MTB) isolates (n=692) from Mpumalanga province was assessed. In total, 692 (64%) MTB strains from cases with...

  • TB prevention in HIV patients.  // Caribbean Health;Oct2000, Vol. 3 Issue 3, p24 

    The article offers information on the alternative methods to prevent tuberculosis in patients with Human Immunodeficiency Virus (HIV) infection. The emergence of isoniazid resistance has made it important to develop clinical substitute of prophylaxis. Two months of rifampicin and pyrazinamide is...

  • Consistency of standard laboratory strain Mycobacterium tuberculosis H37Rv with ethionamide susceptibility testing. R., Lakshmi; Kumar, Vanaja; Rahman, Fathima; Ramachandran, Ranjani // Indian Journal of Medical Research;May2012, Vol. 135 Issue 5, p672 

    Drug susceptibility pattern of standard Mycobacterium tuberculosis strain H37Rv showed discrepancy in minimum inhibitory concentration method for ethionamide and consistent results were obtained for the other second line drugs namely, kanamycin and ofloxacin. It is, therefore, necessary to...

  • Primary Drug Resistance and Molecular Epidemiology of the Mycobacterium tuberculosis Strains Isolated in the Kelkit Valley. Bulut, Yunus; Yenişehirli, Gülgün; Otlu, Baris; Seyfikli, Zehra; Celikel, Serhat; Yilmaz, Ayşe; Inönü, Handan // Turkish Journal of Medical Sciences;2009, Vol. 39 Issue 1, p101 

    Aim: The aim of this study was to determine the primary drug resistance rates and genotypes of resistant Mycobacterium tuberculosis strains isolated in the Kelkit Valley. Materials and Methods: Primary resistance to isoniazid (INH), rifampicin (RIF), ethambutol (ETB), and streptomycin (SM) was...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics