Conclusion and future perspectives on antifungal stewardship

Aguado, Jose María; Silva, Jose Tiago; Bouza, Emilio
November 2016
Journal of Antimicrobial Chemotherapy (JAC);2016 Supplement, Vol. 71, pii43
Academic Journal
journal article
The article reflects on invasive fungal disease (IFD) that consists of various fungal infections including candidiasis to aspergillosis, and cryptococcosis to mucormycosis. It cites a study which reveals that a combination of serum galactomannan (GM) assay and polymerase chain reaction (PCR)-based detection of Aspergillus DNA in blood was associated with an earlier diagnosis of invasive aspergillosis.


Related Articles

  • Estimated Incidence of Antimicrobial Drug-Resistant Nontyphoidal Salmonella Infections, United States, 2004-2012. Medalla, Felicita; Gu, Weidong; Mahon, Barbara E; Judd, Michael; Folster, Jason; Griffin, Patricia M; Hoekstra, Robert M // Emerging Infectious Diseases;Jan2016, Vol. 22 Issue 1, p29 

    Salmonella infections are a major cause of illness in the United States. The antimicrobial agents used to treat severe infections include ceftriaxone, ciprofloxacin, and ampicillin. Antimicrobial drug resistance has been associated with adverse clinical outcomes. To estimate the incidence of...

  • Salicylate induces an antibiotic efflux pump in Burkholderia cepacia complex genomovar III (B. cenocepacia). Nair, Bindu M.; Cheung Jr., K-John; Griffith, Adam; Burns, Jane L.; Cheung, K-John Jr // Journal of Clinical Investigation;Feb2004, Vol. 113 Issue 3, p464 

    An antibiotic efflux gene cluster that confers resistance to chloramphenicol, trimethoprim, and ciprofioxacin has been identified in Burkbolderia cenocepacia (genomovar III), an important cystic fibrosis pathogen. Five open reading Frames have been identified in the cluster. There is apparently...

  • Invasive fungal diseases in children with hematological malignancies and stem cell transplant recipients. Molina, José Ramón; Rojas, R.; Serrano, J.; Gómez, P. // Journal of Hematological Malignancies;Dec2012, Vol. 2 Issue 4, p1 

    Invasive Fungal Disease (IFD) remains a major cause of morbidity and mortality in patients with hematological malignancies or undergoing stem cell transplantation. New surrogate markers of IFD -galactomannan antigen, β-D-glucan, fungal polymerase chain reaction...-and the availability of...

  • The Fight Against Multidrug-Resistant Bacteria. Deak, Dalia; Powers, John H.; Outterson, Kevin; Kesselheim, Aaron S. // Annals of Internal Medicine;1/3/2017, Vol. 166 Issue 1, p79 

    A response from the authors of the article "Progress in the fight against multidrug-resistant bacteria? A review of U.S. Food and Drug Administration-approved antibiotics,2010-2015" published in a 2016 issue of "Annals of Internal Medicine" is presented.

  • Thiazide-induced hypocalciuria is accompanied by a decreased expression of Ca2+ transport proteins in kidney. Nijenhuis, Tom; Hoenderop, Joost G.J.; Loffing, Johannes; Van Der Kemp, Annemiete W.C.M.; Van Os, Carel H.; Bindels, René J.M.; Bindels, René J M // Kidney International;Aug2003, Vol. 64 Issue 2, p555 

    Introduction: Thiazide diuretics have the unique characteristic of increasing renal Na+ excretion, while decreasing Ca2+ excretion. However, the molecular mechanism responsible for this thiazide-induced hypocalciuria remains unclear. The present study investigates the effect of...

  • Aspergillus ustus infections among transplant recipients. Panackal, Anil A.; Imhof, Alexander; Hanley, Edward W.; Marr, Kieren A. // Emerging Infectious Diseases;Mar2006, Vol. 12 Issue 3, p403 

    Aspergillus ustus is a mold that rarely infects humans; only 15 systemic cases have been reported. We report the first outbreak of invasive infection caused by A. ustus among hematopoietic stem cell transplant (HSCT) recipients. Six patients with infections were identified; 3 infections each...

  • Molecular analysis of fluoroquinolone-resistant Salmonella Paratyphi A isolate, India. Nair, Satheesh; Unnikrishnan, Madhulika; Turner, Keith; Parija, Subash Chandra; Churcher, Carol; Wain, John; Harish, Belgode Narasimha; Harish, Narasimha // Emerging Infectious Diseases;Mar2006, Vol. 12 Issue 3, p489 

    Salmonella enterica serovar Paratyphi A is increasingly a cause of enteric fever. Sequence analysis of an Indian isolate showed a unique strain with high-level resistance to ciprofloxacin associated with double mutations in the DNA gyrase subunit gyrA (Ser83-->Phe and Asp87-->Gly) and a mutation...

  • Fluoroquinolone-resistant Escherichia coli, Indonesia. Kuntaman, Kuntaman; Sri Lestari, Endang; Severin, Juliëtte A.; Kershof, Irma M.; Mertaniasih, Ni Made; Purwanta, Marijam; Hadi, Usman; Johnson, James R.; Van Belkum, Alex; Verbrugh, Henri A.; Lestari, Endang Sri; Severin, Juliëtte A; Antimicrobial Resistance in Indonesia, Prevalence and Prevention Study Group // Emerging Infectious Diseases;Sep2005, Vol. 11 Issue 9, p1363 

    In a recent, population-based survey of 3,996 persons in Indonesia, fluoroquinolone (FQ)-resistant Escherichia coli was prevalent in the fecal flora of 6% of patients at hospital admission and 23% of patients at discharge, but not among healthy relatives or patients visiting primary healthcare...

  • Persistence of resistant Staphylococcus epidermidis after single course of clarithromycin. Sjölund, Maria; Tano, Eva; Blaser, Martin J.; Andersson, Dan I.; Engstrand, Lars; Sjölund, Maria // Emerging Infectious Diseases;Sep2005, Vol. 11 Issue 9, p1389 

    We examined how a common therapy that includes clarithromycin affects normally colonizing Staphylococcus epidermidis. Samples from the nostrils of 5 patients receiving therapy were collected before, immediately after, 1 year after, and 4 years after treatment. From each patient and sample, S....


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics