TITLE

Epidemiology, evolution, and future of the HIV/AIDS pandemic

AUTHOR(S)
Levin, B R; Bull, J J; Stewart, F M
PUB. DATE
May 2001
SOURCE
Emerging Infectious Diseases;May/Jun2001, Vol. 7 Issue 3, p505
SOURCE TYPE
Academic Journal
DOC. TYPE
journal article
ABSTRACT
We used mathematical models to address several questions concerning the epidemiologic and evolutionary future of HIV/AIDS in human populations. Our analysis suggests that 1) when HIV first enters a human population, and for many subsequent years, the epidemic is driven by early transmissions, possibly occurring before donors have seroconverted to HIV-positive status; 2) new HIV infections in a subpopulation (risk group) may decline or level off due to the saturation of the susceptible hosts rather than to evolution of the virus or to the efficacy of intervention, education, and public health measures; 3) evolution in humans for resistance to HIV infection or for the infection to engender a lower death rate will require thousands of years and will be achieved only after vast numbers of persons die of AIDS; 4) evolution is unlikely to increase the virulence of HIV; and 5) if HIV chemotherapy reduces the transmissibility of the virus, treating individual patients can reduce the frequency of HIV infections and AIDS deaths in the general population.
ACCESSION #
119413622

 

Related Articles

  • Same sex relationships and HIV/AIDS in Africa: Need for Research and programmatic focus. Okonofua, Friday // African Journal of Reproductive Health;Dec2012, Vol. 16 Issue 4, p9 

    The author reflects on the research conducted by researcher Adebajo and her colleagues regarding the same-sex relationships in Africa. The author states the research shows the possibility of opening up debate and conduct empirical research in less receptive communities. The author notes the high...

  • Unprotected sex following HIV testing among women in Uganda and Zimbabwe: short- and long-term comparisons with pre-test behaviour. Turner, Abigail Norris; Miller, William C.; Padian, Nancy S.; Kaufman, Jay S.; Behets, Frieda M.; Chipato, Tsungai; Mmiro, Francis A.; Salata, Robert A.; Morrison, Charles S. // International Journal of Epidemiology;Aug2009, Vol. 38 Issue 4, p997 

    Background: Despite widespread condom promotion for HIV prevention, prospective measurement of condom use before and after HIV testing is infrequent.Methods: We analysed data from a prospective study of hormonal contraception and HIV acquisition among Zimbabwean and...

  • Youth and HIV/AIDS in Africa: A Call for Effective Policies and Programs. Odaga, Adhiambo // African Journal of Reproductive Health;Jun2012, Vol. 16 Issue 2, p17 

    The author reflects on the need for effective policies and programs to address HIV and AIDS in youth in Africa. The author suggests that African youth are vulnerable to acquiring HIV and AIDS and that the prevalence of the diseases among African youth is 2.3%. The author argues that there is a...

  • La Jeunesse et le VIH/SIDA en Afrique : Demande des politiques et de programmes efficaces. Odaga, Adhiambo // African Journal of Reproductive Health;Jun2012, Vol. 16 Issue 2, p20 

    The author reflects on the need for effective policies and programs to address HIV and AIDS in youth in Africa. The author suggests that African youth are vulnerable to acquiring HIV and AIDS and that the prevalence of the diseases among African youth is 2.3%. The author argues that there is a...

  • HIV-1 infection among intravenous drug users in Manhattan, New York City, from 1977 through 1987. Des Jarlais, Don C.; Friedman, Samuel R.; Novick, David M.; Sotheran, Jo L.; Thomas, Pauline; Yancovitz, Stanley R.; Mildvan, Donna; Weber, John; Kreek, Mary Jeanne; Maslansky, Robert; Bartelme, Sarah; Spira, Thomas; Marmor, Michael; Des Jarlais, D C; Friedman, S R; Novick, D M; Sotheran, J L; Thomas, P; Yancovitz, S R; Mildvan, D // JAMA: Journal of the American Medical Association;2/17/89, Vol. 261 Issue 7, p1008 

    Intravenous drug users are the second largest group to develop the acquired immunodeficiency syndrome, and they are the primary source for heterosexual and perinatal transmission in the United States and Europe. Understanding long-term trends in the spread of human immunodeficiency virus among...

  • Cross-national HIV infection control practices and fear of AIDS: a comparison between Nigeria and the USA. Essien, Ekere James; Ross, Michael W.; Meremikwu, Martins; Essien, E J; Ross, M W; Ezedinachi, E N; Meremikwu, M // International Journal of STD & AIDS;Dec1997, Vol. 8 Issue 12, p764 

    Fears about occupational transmission of HIV may have a significant impact on the behaviour of health care workers and on infection control practices. We investigated the relationships between fear of AIDS and infection control practices in health care workers in major university teaching...

  • Cohort profile: the TREAT Asia pediatric HIV observational database. Kariminia, Azar; Chokephaibulkit, Kulkanya; Pang, Joselyn; Lumbiganon, Pagakrong; Hansudewechakul, Rawiwan; Amin, Janaki; Kumarasamy, Nagalingeswaran; Puthanakit, Thanyawee; Kurniati, Nia; Nik Yusoff, Nik Khairulddin; Saphonn, Vonthanak; Fong, Siew Moy; Razali, Kamarul; Nallusamy, Revathy; Sohn, Annette H; Sirisanthana, Virat // International Journal of Epidemiology;Feb2011, Vol. 40 Issue 1, p15 

    No abstract available.

  • Assessing the impact of national anti-HIV sexual health campaigns: trends in the transmission of HIV and other sexually transmitted infections in England. Nicoll, Angus; Hughes, Gwenda; Donnelly, Mary; Livingstone, Shona; de Angelis, Daniela; Fenton, Kevin; Evans, Barry; Gill, O. Noël; Catchpole, Mike; Nicoll, A; Hughes, G; Donnelly, M; Livingstone, S; De Angelis, D; Fenton, K; Evans, B; Gill, O N; Catchpole, M // Sexually Transmitted Infections;Aug2001, Vol. 77 Issue 4, p242 

    Objective: To assess the impact of the sexual component of AIDS and HIV campaigns on transmission of HIV and other sexually transmitted infections (STIs).Design: Comparison of time series data.Setting: England, 1971-1999.Outcome Measures: HIV...

  • The potential of task-shifting in scaling up services for prevention of mother-to-child transmission of HIV: a time and motion study in Dar es Salaam, Tanzania. Naburi, Helga; Ekström, Anna Mia; Mujinja, Phares; Kilewo, Charles; Manji, Karim; Biberfeld, Gunnel; Sando, David; Chalamila, Guerino; Bärnighausen, Till // Human Resources for Health;5/26/2017, Vol. 15, p1 

    Background: In many African countries, prevention of mother-to-child transmission of HIV (PMTCT) services are predominantly delivered by nurses. Although task-shifting is not yet well established, community health workers (CHWs) are often informally used as part of PMTCT delivery....

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics