Death begets failure in the heart

Foo, Roger S. Y.; Mani, Kartik; Kitsis, Richard N.
March 2005
Journal of Clinical Investigation;Mar2005, Vol. 115 Issue 3, p565
Academic Journal
journal article
Recently, low--but abnormal--rates of cardiomyocyte apoptosis have been observed in failing human hearts. Genetic and pharmacological studies suggest that this cell death is causally linked to heart failure in rodent models. Herein, we review these data and discuss potential therapeutic implications.


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