Placebo and analgesic nitrous oxide for treatment of the alcohol withdrawal state

Gillman, Mark A.; Lichtigfeld, Frederick J.; Gillman, M A; Lichtigfeld, F J
November 1991
British Journal of Psychiatry;Nov91, Vol. 159, p672
Academic Journal
journal article
We present evidence that analgesic (as distinct from anaesthetic) nitrous oxide is superior to placebo in the treatment of the alcohol withdrawal state. 'Carbogen' as a placebo is as effective as oxygen or medical air. However, placebo alone offers a means of treating the alcohol withdrawal state with a minimum of pharmacological intervention. Analgesic nitrous oxide for those not responding to placebo is a very rapid, effective, and extremely safe treatment which also reduces the use of highly addictive sedative pharmacological agents. This therapy also provides a rapid method of screening those patients requiring intensive monitoring and treatment in hospital from those who might benefit from out-patient therapy alone.


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