Infant HIV-1 Vaccines

Fouda, Genevieve G.; Cunningham, Coleen K.; Permar, Sallie R.
April 2015
JAMA: Journal of the American Medical Association;4/21/2015, Vol. 313 Issue 15, p1513
Academic Journal
The article discusses a program by the World Health Organization (WHO) to prevent mother-to-child transmission of human immunodeficiency virus type 1 (HIV-1) through maternal antiretroviral therapy (ART). Topics include the program's poor performance record; reasons that maternal ART can be ineffective, such as late-starting care, nonadherence, and acute infection while brestfeeding; and a call for infant HIV-1 vaccine trials to be reinstated to create an alternative to maternal ART.


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